Obstetrics & Gynecology Science

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Original Article
Korean J Obstet Gynecol. 2006;49(9):1902-1907. Published online September 1, 2006.
Clinical analysis of synchronous primary neoplasms of the female reproductive tract.
Seo Yun Tong, Yong Sek Lee, Jong Sup Park, Jun Mo Lee, Seung Eun Namkoong
Department of Obstetrics and Gynecologic, College of Medicine, The Catholic University of Korea, Seoul, Korea. jspark@catholic.ac.kr
Abstract
OBJECTIVE
A histopathologic review of synchronous primary neoplasms of the female reproductive tract was presented and the possible correlation among discrete tumor subsets, natural history, and survival was evaluated. METHODS: Between 2000 and 2005, 20 patients with synchronous primary cancers of the gynecologic malignancy were identified. Clinical and pathologic informations were obtained from medical records. Kaplan-Meier survival analysis was performed. RESULTS: The patients with Synchronous primary malignancies constituted 0.63% of all genital malignancies. The most frequently observed synchronous neoplasms were those of the ovary with the endometrium (40%). The mean age of patient with synchronous ovarian and endometrial cancer was 45.2 years. 8 patients underwent the hysterectomy with bilateral salpingo-oophorectomy and adjuvant therapy. The mean survival is 57 months (SE 10.0, 95% Confidence interval 37-77). CONCLUSION: Synchronous ovarian and endometrial cancers were detected in relatively early age and the prognosis was favorable.

Keywords :Synchronous neoplasm;Endometrial cancer;Ovarian cancer;Prognosis

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