Obstetrics & Gynecology Science

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Original Article
Korean J Obstet Gynecol. 2004;47(5):957-965. Published online May 1, 2004.
The Effect on IVF-ET Outcomes of Intramural Myomas.
Ae Hyun Lee, Byeong Yun Kim, Gun Oh Chong, Kee Sang Park, Sung Yob Kim, Taek Hoo Lee, Sang Sik Chun
1Department of Obstetrics and Gynecology, College of Medicine, Kyungpook National University, Korea.
2Division of Infertility Clinic, Kyungpook National University Hospital, Taegu, Korea.
3Department of Obstetrics and Gynecology, College of Medicine, Cheju National University, Cheju, Korea.
Abstract
OBJECTIVE
The aim of this study was to assess the effect of intramural uterine myoma in patients with a normal endometrial cavity on IVF-ET cycle outcome. This study was also investigated to find out whether medical supression or myomectomy needs to precede to IVF-ET. METHODS: The subjects were 300 infertile patients who got IVF-ET from January 1999 to December 2002 at the Department of Obstetrics and Gynecology in Kyungpook National University Hospital, and they were divided into myoma group of 97 patients and non-myoma group of 203 ones. This study group did not include patients found to have large myoma (>or= 7 cm), or myoma distorting the uterine cavity. RESULTS: Compared with the results of IVF-ET according to the presence of intramural uterine myoma, pregnancy rate and implantation rate between two groups had no statistically significant differences (p>0.05). Further comparisons within the myoma group showed no difference in pregnancy rate by number of myomas or site of myomas (p>0.05). CONCLUSION: Intramural uterine myoma not distorting the uterine cavity is considered to have no effect on the outcome of IVF-ET and no difference in the pregnancy rate according to the number of myomas or site of myomas. Therefore, these findings suggest that medical treatments or myomectomy before IVF-ET is not necessary to those infertile patients with intramural uterine myomas not distorting the uterine cavity.

Keywords :Intramural myoma;Infertility;IVF-ET

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