Obstetrics & Gynecology Science

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Case Report
Korean J Obstet Gynecol. 2003;46(10):2079-2082. Published online October 1, 2003.
A Case of Thrombotic Thrombocytopenic Purpura in Pregnancy.
Jong Min Kim, Hae Hyeog Lee, Tae Hee Kim, Hyeong Mun Kim, So Jin Yeo, Kye Hyun Nam, Yil Ku Shim, Kwon Hae Lee
Department of Obstetrics and Gynecology, College of Medicine, Soonchunhyang University, Bucheon, Korea.
Abstract
Thrombotic thrombocytopenic purpura (TTP) is quiet rare, with 1 of 25,000 delivery and complicating pregnancy is associated with high maternal mortality and long-term morbidity. Unfortunately the clinical appearance of thrombotic thrombocytopenic purpura is similar with the syndrome of hemolysis, elevated liver enzyme, and low platelet (HELLP), but the treatment of this differs from that of the HELLP syndrome or acute fatty liver of pregnancy, therefore accurate diagnosis is essential for optimal therapy. The survival of this disorder has been improved due to aggressive treatment with plasma transfusion or plasmapheresis. We have experienced a case of thrombotic thrombocytopenic purpura confused with HELLP syndrome of preeclampsia, so we report it with a brief review of literature.

Keywords :Thrombotic thrombocytopenic purpura;HELLP syndrome;Plasmapheresis

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