Obstetrics & Gynecology Science

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Original Article
Korean J Obstet Gynecol. 2003;46(9):1702-1706. Published online September 1, 2003.
Clinical Significance of Multiple Serum Tumor Markers in the Detection of Ovarian Carcinoma.
Ho Sun Choi, Yoon Sang Oh, Moon Kyong Cho, Myoung Seon Kang, Woo Dae Kang, Sang Hyun Park, Kwang Su Lee, Jin A Ha, Myoung Sook Jo, Seok Mo Kim
Department of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, Korea.
Abstract
OBJECTIVE
This study evaluated the possible role of 2 additional tumor markers to CA125 in discriminating between benign and malignant ovarian tumors. METHODS: Serum samples from 1,346 patients were obtained on seven days before operation. All patients underwent surgery for ovarian tumors. Serum levels of 3 tumor markers were compared to histology. Concentrations of tumor markers (CA125, CA72-4, CA19-9) were detected by enzyme immuno- or immunoradiometric assays. Normal range of these markers was defined as CA125
Keywords :Serum tumor markers;CA125;CA72-4;CA19-9;Ovarian tumors

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