Obstetrics & Gynecology Science

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Original Article
Korean J Obstet Gynecol. 2003;46(4):746-751. Published online April 1, 2003.
Umbilical Nucleated Red Blood Cell Counts and Perinatal Outcome According to Doppler End-Diastolic Velocity in Severe Preeclampsia.
Joon Hwan Oh, Yun Kyoung Lim, Hee Jong Lee, Haeng Soo Kim, Jeong In Yang, Hee Sug Ryu, Kie Suk Oh
Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Korea.
Abstract
OBJECTIVE
To assess the umbilical nucleated red blood cell counts and perinatal outcomes according to umbilical artery Doppler end diastolic velocity in severe preeclampsia. MATERIALS AND METHODS: A prospective case-control study comparing 42 severe preeclampsia patients who had present umbilical artery end diastolic velocity with 7 severe preeclampsia patients who absent end diastolic velocity for umbilical nucleated red blood cell counts and perinatal outcomes. RESULTS: Those with absent end diastolic velocity did not have significantly greater nucleated red blood cell counts, but they had increased hemoglobin, hematocrit. These newborn had significantly lower birth weight, increased Cesarean section rate for fetal distress and been more frequently admitted to the neonatal intensive care unit. These newborn also had significantly increased intracranial hemorrhage,assisted ventilation and longer hospital days. CONCLUSION: No correlation with nucleated red blood cell counts and chronic fetal hypoxia were presented. However further study with more expanded cases for the role of nucleated red blood cell counts as a marker of fetal hypoxia will be needed.

Keywords :Nucleated red blood cell counts;Doppler end diastolic velocity;Preeclampsia

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