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Original Article
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Korean J Obstet Gynecol. 2001;44(5):861-866. Published online May 1, 2001.
- Prevalence of Autoantibodies in Patients with Endometriosis.
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Seung Yup Ku, Young Min Choi, Byoung Joon Jung, Chang Suk Suh, Seok Hyun Kim, Jung Gu Kim, Shin Yong Moon, Jin Yong Lee
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1Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea.
2Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University, Seoul, Korea.
- Abstract
- OBJECTIVES
To assess the prevalence of autoantibodies in patients with endometriosis MATERIALS AND METHODS: The prevalence of autoantibodies were investigated in 93 patients with endometriosis diagnosed by laparoscopy or laparotomy. Autoantibodies, such as antithyroglobulin antibody, antimicrosomal antibody, antinuclear antibody (ANA), antiphospho -lipid antibody (APA), lupus anticoagulant (LAC), anti-dsDNA, and rheumatoid factor, were measured in sera of the subjects. The prevalence and distribution of autoantibodies were analyzed according to the stage of endometriosis. RESULTS: All seven autoantibodies were checked in 73 patients out of 93 patients. Autoantibodies were identified in 23 of 73 patients with endometriosis (31.5%). Antibodies detected were antithyroglobulin antibody (15.2%), ANA (12.0%), antimicrosomal antibody (8.7%), anti-dsDNA (5.4%), and rheumatoid factor (4.4%), APA (2.2%) and LAC (1.3%). The prevalence of autoantibodies did not differ by the AFS stage. CONCLUSION: Autoantibodies were detected in about one-third of patients with endometriosis. The prevalence of autoantibodies did not differ by the stage.
Keywords :Autoantibody;Prevalence;Endometriosis;Stage
