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Case Report
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Korean J Obstet Gynecol. 2012;55(10):772-776. Published online October 10, 2012.
DOI: https://doi.org/10.5468/KJOG.2012.55.10.772
- A case of ovarian dysgerminoma with gonadal dysgenesis in 29-year-old woman with 46,XX karyotype.
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So Yeon Yoon, Hyang Gi Park, Jin Yi Kuk, Soon Ae Oak, Jong Hoon Park
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1Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. soyeon.yoon@samsung.com
2Department of Pathology, Ilsin Christian Hospital, Busan, Korea.
3Department of Obstetrics and Gynecology, Ilsin Christian Hospital, Busan, Korea.
- Abstract
- Gonadal dysgenesis occurs in rare case of ovarian tumor. Most tumors associated with gonadal dysgenesis were gonadoblastomas and dysgerminomas. In addition, premature ovarian insufficiency associated with these ovarian tumors in normal chromosomal type had not reported in many cases. A 29-year-old nulligravida woman who was concurrented with ovarian dysgerminoma and fibroma is presented. Measurements were made on serum lactate dehydrogenase, CA-125, CA 19-9 and pelvis ultrasonography and computed tomography. The clinical stage was IA and right salpingo-oophorectomy and wedge resection of the left ovary were done. On laboratory finding after operation on her serum follicular stimulating hormone was increased and E2 was decreased. The result of chromosomal analysis was 46,XX, normal. We represent here with brief review of literature one case of gonadal dysgenesis in nulligravida woman, associated with dysgerminoma, with normal karyotype.
Keywords :Dysgerminoma;Gonadal dysgenesis;Normal karyotype
