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Obstet Gynecol Sci > Volume 53(10); 2010 > Article
Korean Journal of Obstetrics & Gynecology 2010;53(10):888-893.
DOI: https://doi.org/10.5468/kjog.2010.53.10.888    Published online October 1, 2010.
The efficacy of a real-time optoelectronic device as a diagnostic tool of over cervical intraepithelial neoplasia 1 lesion.
Hyeong Soo Lim, Min Jung Kim, Kyung Eui Park, Hyun Hoon Chung, Noh Hyun Park, Yong Sang Song, Soon Beom Kang
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea. ksboo308@plaza.snu.ac.kr
Abstract
OBJECTIVE
The purpose of this study was to evaluate the sensitivity, specificity and accuracy of a real-time optoelectronic device (TruScreen) as a diagnostic tool of cervical intraepithelial neoplasia (CIN) or cervical cancer. METHODS: Two hundred ninety two patients who had been presented with previously abnormal Papanicolaou (Pap) smear or abnormal colposcopic findings between February 2009 and September 2009 were analyzed. The sensitivities, specificities and accuracies of TruScreen and liquid-based cytology were evaluated. RESULTS: As a diagnostic tool of CIN, carcinoma in situ (CIS), and cervical cancer, TruScreen appeared sensitive enough compared with liquid-based cytology (82.8% vs 75.9%), but the difference is statistically not significant (P=0.687). Specificity and accuracy of TruScreen were similar to those of liquid-based cytology (specificity 81.4% vs 83.3%, accuracy 81.5% vs 82.5%). CONCLUSION: The present study suggests that the TruScreen could be an option as a tool of screening test in CIN, CIS, and cervical cancer and also be used combined with Pap smear.
Key Words: Cervical intraepithelial neoplasia, Cervical cancer, TruScreen, Liquid-based cytology


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