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Korean Journal of Obstetrics & Gynecology 2007;50(6):887-892.
Published online June 1, 2007.
Prognostic factors in recurrent cervical cancer patients with pulmonary metastasis.
Mi Ok Lyu, Ho Yeon Kim, Jong Hyuck Yoon, Suk Joon Chang, Jung Pil Lee, Ki Hong Chang, Hee Sug Ryu, Jae Hoon Kim
1Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Korea. drchang@ajou.ac.kr
2Department of Obstetrics and Gynecology, Young Dong Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Abstract
OBJECTIVE
To characterize prognostic factors in patients with pulmonary metastasis in recurrent cervical cancer. METHODS: The records of 2,042 patients treated for cervical cancer from 1994 to 2004 at two institutions were retrospectively reviewed. Twenty-five (1.04%) patients had pulmonary lesions consistent with metastatic cervical cancer. The data were analyzed retrospectively and reviewed for patient characteristics. RESULTS: Patients were treated with chemotherapy, radiotherapy only, chemoradiotherapy, surgery, and conservative treatment. There were no significant differences in survival rates between each treatment method (p=0.3410). Mean survival after treatment of pulmonary metestasis was 23 months. Histologic type, lymph node metastasis, other organ metastasis, and pretreatment SCC level were not significant prognostic factors, but FIGO stage (p=0.039) and disease-free interval (p=0.033) were significant factors. CONCLUSION: This study revealed that FIGO stage and disease-free interval were independent prognostic factors of pulmonary metestasis in recurrent cervical cancer.
Key Words: Cervical cancer, Pulmonary metastasis, Prognosis


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