A Case of Endometrioid Stromal Sarcoma of ovary.

Song, Jeong Ho; Jeon, Sung Chul; Kang, Ji Hoon; Han, Kyun; Lee, Hyun Sung; Hwang, In Soo; Park, Cheol Hong; Lee, Mi Sun

Case Report

Korean Journal of Obstetrics & Gynecology 2003;46(1):188-191.
Published online January 1, 2003.

A Case of Endometrioid Stromal Sarcoma of ovary.

Jeong Ho Song, Sung Chul Jeon, Ji Hoon Kang, Kyun Han, Hyun Sung Lee, In Soo Hwang, Cheol Hong Park, Mi Sun Lee

¹Department of Obstetrics and Gynecology, Sun General Hospital, DaeJeon, Korea.
²Department of Pathology, Sun General Hospital, DaeJeon, Korea.

Abstract

Endometrioid stromal sarcoma of ovary is so rare that it has been reported 45 cases in the world. Endometrioid stromal sarcoma of ovary is concomitant with endometriosis at 40%, with same tumor in uterus at 30%. The age of pateint is between 11 and 76, half of them are fifties and sixties. Most frequent presenting symptom is abdominal distension and abdominal pain. Surgery, chemotherapy, radiotherapy, progesterone was helpful, but any management do not result in conclusion because of rarity of cases. Clinical course is indolent because lesion is well-differentiated and grows slowly, so only cytoreductive surgery will be effective. Progesterone may be effective in residual or recurrent low-grade endometrioid stromal sarcoma of ovary. If endometriotic tissue is origin of tumor, estrogen play a role in malignant transformation. We had experienced a case of endometrioid stromal sarcoma of ovary of 42 years old woman. We managed by TAH and BSO, radiotherapy, progesterone therapy. Until now no recurrence was found for 15 months. So, we report this case with review of the literature.

Key Words: Endometrioid stromal sarcoma of ovary, Endometriosis, Progesterone