A Case of Juvenile Granulosa Cell Tumor of the Ovary.

Hwang, Myung Joong; Choi, Hyun Il; Cha, Dong Soo; Lim, Ji Hoon; Hong, Min; Lee, Young Jin

Case Report

Korean Journal of Obstetrics & Gynecology 2002;45(12):2295-2298.
Published online December 1, 2002.

A Case of Juvenile Granulosa Cell Tumor of the Ovary.

Myung Joong Hwang, Hyun Il Choi, Dong Soo Cha, Ji Hoon Lim, Min Hong, Young Jin Lee

Department of Obstetrics and Gynecology, Yonsei University, Wonju College of Medicine, Wonju, Kangwon-do, Korea.

Abstract

Juvenile granulosa cell tumor is a well-known sex-cord stromal ovarian neoplasm different in appearance and behavior from the adult granulosa cell tumor and occurs most (80%) frequently in the first two decades. The prognosis of juvenile granulosa cell tumor in children is good in most cases, but correlated with stage, size, the presence of ruptures, the grade of nuclear atypia, the degree of mitotic activity. The surgery remains the principal line of treatment for low stage juvenile granulosa cell tumor in children, but for those patient with high stage juvenile granulosa cell tumor or recurrence, the best treatment has yet to be determined and tumor sensitivity to radiation therapy and chemotherapy is not clearly. We present a case of juvenile granulosa cell tumor with brief review of literatures.

Key Words: Juvenile granulosa cell tumor, Sex-cord stromal tumor