A Case of Agenesis of Corpus Callosum with Chromosome anomaly.

Park, Jung Hui; Lee, Gui Se Ra; Kim, Sa Jin; Shim, Sang In; Kim, So Young; Yoo, Won Jong; Baik, Eun Jeong; Shin, Jong Chul; Kim, Soo Pyung

Case Report

Korean Journal of Obstetrics & Gynecology 2000;43(1):137-140.
Published online January 1, 2001.

A Case of Agenesis of Corpus Callosum with Chromosome anomaly.

Jung Hui Park, Gui Se Ra Lee, Sa Jin Kim, Sang In Shim, So Young Kim, Won Jong Yoo, Eun Jeong Baik, Jong Chul Shin, Soo Pyung Kim

Abstract

The corpus callosum consists of white fibers connecting the cerebral hemispheres. Agenesis of the corpus callosum is an uncommon congenital anomaly which is easily diagnosed in the postnatal period by ultrasound and computed tomographic scan or MRI, but its prenatal sonographic diagnosis is difficult because of fetal head positioning and limiting trans-axial scans. We experienced a case of agenesis of the corpus callusum with chromosomal anomaly. The prenatal sonographic findings are ventricular abnormalities that demonstrated dilatation of lateral ventricles and disproportionate enlargement of the occipital horns, which were suggestive findings for the corpus callosal agenesis. We could confim the diagnosis of the corpus callosal agenesis with chromosome anomaly by postnatal MRI and chromosome analysis.

Key Words: agenensis of corpus callosum, chromosome anomaly