Placental mesenchymal dysplasia associated with severe preeclampsia: A case report.

Na, Eun Duc; Lee, Kyoung Jin; Kim, Myung Joo; Yi, Hyo Jin; Kim, Ji Young

doi:2011.54.8.459

Obstet Gynecol Sci > Volume 54(8); 2011 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2011;54(8):459-463.
DOI: https://doi.org/10.5468/KJOG.2011.54.8.459 Published online August 1, 2011.

Placental mesenchymal dysplasia associated with severe preeclampsia: A case report.

Eun Duc Na, Kyoung Jin Lee, Myung Joo Kim, Hyo Jin Yi, Ji Young Kim

¹Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, Korea. jlee3575@hanmail.net
²Department of Pathology, CHA Gangnam Medical Center, CHA University, Seoul, Korea.

Abstract

Placental mesenchymal dysplasia (PMD) is a relatively recently recognized, rare placental vascular anomaly characterized by placentomegaly and grapelike vesicles that may coexist with a normal fetus. Ultrasonography performed at 16 weeks of gestation revealed multiple cysts in the placenta along with a morphologically normal fetus. At 24 weeks of gestational age, severe preeclampsia symptoms were seen. And sonographically intrauterine growth restriction (IUGR) and oligohydroamnios were noted. Based on the diagnosis of severe preeclampsia, termination of pregnancy was done. After termination, histopathologic examination of the placenta showed numerous grape-like cystic vesicles throughout the entire placenta and absence of trophoblastic proliferation and pseudoinclusions. We have described a pregnancy complicated with PMD associated with mid-trimester severe preeclampsia, IUGR and oligohydroamnios.

Key Words: Placental mesenchymal dysplasia, Pre-eclampsia